Modulates Cholinergic and Glutamatergic Systems While its exact mechanisms of action are not completely understood, oxiracetam’s actions are similar to those of other racetam-class drugs, which enhance cognitive function by stimulating specific neurotransmitter receptor sites and directly modulating the production and release of certain neurotransmitters. Studies also indicate that it may promote wakeful alertness by enhancing blood flow to and within the brain, improving energy metabolism. In animal testing, it was shown to promote arousal and inhibit sleep. Oxiracetam is a cholinergic, a substance which releases or responds to the neurotransmitter acetylcholine, and as such acts, as a mild psychostimulant. Mild Stimulant and Promotes Wakefulness In further testing, oxiracetam was also found to alleviate blood-brain barrier dysfunction and protect against ischemic stroke in rats. In animal studies, brain trauma typical of neurological disorders was modeled by introducing neurotoxins known to impair memory formation. The studies indicated that animals given pre-treatment with oxiracetam were resistant to neurotoxicity. Research suggests that oxiracetam may have a significant neuroprotective effect that could potentially block the brain damage associated with Alzheimer’s disease and other forms of dementia. In studies on elderly subjects with primary or multi-infarct dementia, oxiracetam supplementation was shown to stem symptoms of cognitive decline with a particularly marked positive effect on verbal fluency and verbal learning. Oxiracetam’s cognitive enhancement effects, combined with its mild stimulant properties, make it attractive to individuals looking for a combination of focus and energy. Concentration and FocusĪnecdotally, oxiracetam is reported to improve overall concentration and focus, making it easier to learn for extended periods of time without waning interest or attentiveness. This effect may be due to oxiracetam’s ability to improve memory formation and recall speed. Learning Enhancementīoth animal studies and research involving dementia patients indicates that oxiracetam can improve learning ability. Īnimal studies on healthy rodents appear to support these reports. There are no studies on how oxiracetam affects users with normal cognitive ability, but anecdotal evidence indicates that it acts as a powerful memory-boosting nootropic, particularly useful to students taking exams or studying logic-intensive subjects such as math. Oxiracetam’s potential as a memory booster is one of its best known and most studied properties.īoth animal studies and clinical trials on adults with age-related cognitive decline indicate that oxiracetam can improve memory in general, enhancing both memory formation and retention and exerting a significantly positive effect on the speed of recall. Oxiracetam offers a broad range of nootropic benefits, including the following: Improved Memory Oxiracetam is currently unregulated in the US, Canada, Australia, and the UK. Oxiracetam has not been explicitly approved for any specific use by the USFDA. Though there is no documented research on oxiracetam’s effect on young, healthy human subjects, it is a popular nootropic believed by many to enhance memory, learning ability, and overall cognition regardless of age or cognitive condition. Research suggests that oxiracetam is safe and effective in long-term therapy, and may promote and preserve brain health. Clinical trials involving aged patients with cognitive decline indicate oxiracetam may be useful in dementia treatment, and there is even clinical evidence that it can help restore memory. Oxiracetam has been studied as a potential treatment for memory loss related to Alzheimer’s disease and other neurological conditions. Its stimulant properties, which are similar to phenylpiracetam, are powerful enough to promote wakefulness without significantly interfering with normal sleep patterns. Though its chemical structure and mechanisms of action are similar to those of piracetam, oxiracetam is more potent.
ĭeveloped in the 1970s, oxiracetam is a synthetic derivative of piracetam, the original nootropic. It also acts as a mild stimulant that may increase mental energy, alertness, and motivation. Oxiracetam is a potent and popular nootropic that has been shown to enhance a broad range of cognitive processes such as memory, learning capacity, attention, and even verbal fluency. Our evidence-based analysis of Oxiracetam features unique references to scientific papers and anecdotal reports.
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